Ulcerative Colitis Longterm Effects

Ulcerative colitis is a chronic illness characterized by inflammation in the large intestine. When active, the disease causes severe abdominal cramping and bloody diarrhea. The long-term effects of the disease and the medications used to manage it can range from minor physical changes, including acne to very serious conditions, such as an increased risk of colon cancer.

Colon Cancer

According to the National Digestive Diseases Information Clearinghouse, the risk of developing colon cancer increases the longer the disease is in effect and the greater the extent of damage to the colon.

Side Effects From Steroids

Steroids, including Prednisone, are frequently used to manage the disease. Long-term use of these drugs can lead to acne, mood changes, insomnia, weight gain, depression and high blood pressure, to name a few side effects.

Anemia

The long-term, excessive bloody diarrhea characteristic of ulcerative colitis leads to iron-deficiency anemia, which is a lack of iron-rich, healthy red blood cells.

Malnutrition/Dehydration

Each bout of diarrhea causes a loss of vital fluids and nutrients. Dehydration can result if that loss is not replenished with ample amounts of fluids. Malnutrition can occur if additional protein is not consumed.

Arthritis

As the immune system struggles to cope with long-term ulcerative colitis, arthritis, a swelling of the joints, often occurs. The most common symptoms are pain in the knees, ankles and wrists.

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